Fighting Fatigue with NAD+

One of the symptoms of the peri- and menopause that is well established and, indeed, recognised by the Gen M mission is fatigue. This is where life gets really disrupted. Because it’s not just physical weariness, it’s also cognitive exhaustion that makes one feel like a constant six out of ten with an IQ that’s plummeted into single figures. And the meanest thing about all this? It comes at a time in life when physical and mental energy is exactly what you need to maintain performance in the career you’ve climbed, manage the dependency of both kids and parents and enjoy the time you might occasionally find for yourself. 

When the black coffee and Barocca just don’t cut it anymore, it’s useful to take a closer look at how energy is produced and how to start mitigating the impact of falling oestrogen levels on this.


Our bodies generate energy at a cellular level

It’s the mitochondria in our cells that turn nutrients from our food into energy for our body and brain. So much so, the mitochondria are classically described as the “powerhouse of the cell”. Oestrogen is related to this because it plays a role in the function of the mitochondria (how well it works). So, when oestrogen levels fall, this may have a knock-on effect on energy production; the cell isn’t making the same amount of energy from the food you’ve always eaten.

But there is something else going on too...

There’s another natural compound that works on the mitochondria that plays a major role in the production of energy within the cell. It’s called NAD+ and it also declines significantly with age – halving every 20 years. 

Fortunately, there is something that can be done about NAD+ levels...


NAD+ can help boost energy levels

NAD+ is a vital factor in the production of ATP – the energy currency of the body and the brain. In fact, it’s so important that the cell has many ways of making NAD+ including its own recycling mechanism. 

However, with increasing age, the enzymes needed to make and recycle NAD+ decline. Not only that but an increase in inflammation and need for cellular repair as we age drains the NAD+ that is produced – leaving less available for energy production.

The good news is, over the last ten years, an abundance of scientific research has emerged showing that it is possible to address these changes and increase the amount of NAD+ available to the cell for energy production.

And this is where Nuchido TIME+ comes in…


Nuchido TIME+ is proven to increase NAD+

Nuchido TIME+ has been carefully formulated to address the multiple factors associated with NAD+ production, recycling and wastage within the cell. Taken as a supplement, Nuchido TIME+ combines a number of evidence-based ingredients that work together to increase NAD+ production and reduce unnecessary NAD+ consumption – so that more NAD+ is available for energy production.

In our study, Nuchido TIME+ was shown to increase NAD+ by 242% among study participants.


Nuchido TIME+ was created by a team of UK scientists specialising in the science of cellular ageing. Founded by cell biologist Dr Nichola Conlon, Nuchido’s mission is to bring the abundance of scientific research currently sitting in the academic research environment to people so that they can be healthier and more active for longer.

This is why Nuchido is so proud to be one of the founding partners of Gen M; we share a mission of providing reliable information and education to the population and believe that this will have a positive impact on the lives of hundreds of women.

We are offering a 10% discount on first orders for Gen M readers and members using the code GENM at checkout in the summary box.