Clinical Evidence

Do you know that most NAD+ products have no clinical evidence to support their marketing claims? At Nuchido, everything we do is supported by science which is why we have conducted human clinical trials on Nuchido TIME+.

nuchido time+ clinical evidence

At Nuchido we rely on peer-reviewed scientific evidence to support our product - not just anecdotal evidence and testimonials

Our published clinical trials prove that Nuchido TIME+ not only boosts NAD+ but also improves other important markers of cellular health

Nuchido TIME+ is the only NAD+ supplement proven to fix the root causes of NAD+ decline and reverse biological age humans

Nuchido TIME+ improves markers of cellular health and has whole-body benefits

WHOLE-BODY BENEFITS

IMPROVED SKIN HEALTH

NAD+ and SIRT1 are known to influence skin health by regulating inflammation, collagen production and skin cell turnover. We measured markers of skin health with a VISIA facial scanner and found Nuchido TIME+ visibly improved redness and pigmentation following 90 days of supplementation.

WHOLE-BODY BENEFITS

INCREASED ENERGY LEVELS

NAD+ is critical for cellular energy production. In our clinical trial, participants reported a 62% increase in energy levels after 90 days supplementation with Nuchido TIME+.

WHOLE-BODY BENEFITS

ENHANCED SLEEP QUALITY

NAD+ and SIRT1 both have an important role in circadian rhythm and sleep and Nuchido TIME+ was found to significantly improve sleep quality after 90 days supplementation.

WHOLE-BODY BENEFITS

IMPROVED QUALITY OF LIFE

NAD+ is critical to every cell so the benefits of boosting NAD+ can be felt across the whole body. In our clinical trial participants reported an all round improvement in their quality of life (QOL).

CELLULAR BENEFITS

INCREASED NAD+

Nuchido TIME+ is clinically proven to significantly increase NAD+ levels within 7 days. NAD+ is the healthy aging molecule and higher NAD+ levels contribute to cellular health.

CELLULAR BENEFITS

RESTORED NAD+ PRODUCTION

Nuchido TIME+ restores the body's own natural NAD+ production pathway. Declining levels of the NAD+ recycling enzyme NAMPT is the leading cause of age-related NAD+ decline. Nuchido TIME+ was found to increase levels of the NAMPT enzyme after 28 days of supplementation.

CELLULAR BENEFITS

REDUCED INFLAMMATION

Nuchido TIME+ reduces inflammation. Inflammation is a leading cause of cellular aging. Nuchido TIME+ was found to reduce inflammatory cytokines after 28 days of supplementation.

CELLULAR BENEFITS

REDUCED GLYCATION

Nuchido TIME+ reduces glycation. Glycated serum proteins are precursors to advanced glycation end-products (AGES) which are highly correlated with aging and multiple age-related issues. Nuchido TIME+ was found to decrease glycated serum protein after 28 days of supplementation.

CELLULAR BENEFITS

INCREASED LONGEVITY PROTEINS

Nuchido TIME+ increases the longevity protein SIRT1. SIRT1 is a NAD+-dependent enzyme that coordinates many of the health-promoting effects of NAD+. Nuchido TIME+ was found to significantly increase SIRT1 after 28 days of supplementation.

CELLULAR BENEFITS

REVERSAL OF BIOLOGICAL AGE

Your biological age is how old you are on the inside. Nuchido TIME+ was found to reduce biological age by an average of 1.26 years after 28 days of supplementation. The GlycanAge biological age test is available as a consumer kit allowing you to test the efficacy of Nuchido TIME+ yourself.

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NUCHIDO CLINICAL EVIDENCE

Click the button below to read the full research reports of Nuchido's clinical trials

READ OUR CLINICAL EVIDENCE

learn how Nuchido TIME+ can reverse your biological age

Nuchido TIME+ is proven in a human clinical trial to reverse biological age - meaning you really can age backwards from the inside

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SCIENTIFIC PAPERS

Our founder Dr Nichola Conlon is a longevity expert and has been researching NAD+ for many years. Read her peer-reviewed papers on the science of NAD+ restoration.