A smarter way to boost NAD+

At Nuchido we’ve pioneered a way to boost NAD+ that doesn't need NR (Nicotinamide Riboside) or NMN (Nicotinamide mononucleotide) precursors to achieve remarkable results. 

The scientific detail

Our approach is called Systems Pharmacology, which studies biological systems as a complex mix of molecular pathways and processes.

Cellular NAD+ productionis an ideal subject for Systems Pharmacology because boosting NAD+ back to healthy levels requires a multi-targeted or ‘system-wide’ approach.

Nuchido's scientific team has identified the right combination of targets to restore cellular NAD+ production back to youthful levels leading to the development of a breakthrough NAD+ booster called Nuchido TIME+.

The NAD+ salvage pathway

As our cells use NAD+ it gets converted into a 'waste' product called nicotinamide, which is then recycled back into fresh NAD+ by enzymes in the NAD+ salvage pathway. When this recycling process works with youthful efficiency it makes nearly all of the NAD+ our cells need to stay healthy.

Unfortunately older cells don’t have the recycling capacity they once did, which means over time our levels of NAD+ drift downwards as cells struggle to recycle 'waste' nicotinamide back into NAD+.

Topping up NAD+ levels with a precursor like NR or NMN therefore seems like a good idea, but there's a problem. Precursors don't address the multiple issues that cause NAD+ to decline with age. This means old cells with an inefficient NAD salvage pathway don't have enough capacity to convert high doses of many precursors into new NAD+, so they are simply excreted as waste.

To get cellular NAD+ high enough to re-start natural self-repair systems it is important to restore the efficiency of our cells to produce their own NAD+ by restoring the function of the cells to produce and recycle their own NAD+.

Boosting natural NAD+ production

Nuchido TIME+ targets multiple cellular pathways involved in the production and consumption of NAD that become disregulated with age allowing older cells to resume higher levels of natural NAD production.

Our product contains a patented formulation of molecules derived from natural ingredients to correct issues that underly NAD+ decline in older cells. It boosts NAD+ by an average of 242%, which is around four times more than any other intervention currently available.

Nuchido TIME+ represents a more efficient way to boost NAD+. This means it's time to put precursors to one side and focus upon restoring the efficiency of our cells to produce youthful levels of NAD+.

Buy Nuchido TIME+