A growing body of scientific research now suggests one of the best ways to combat ageing is to maintain high levels of cellular NAD+. When your NAD+ levels are high it makes you feel great and boosts the energy you need to keep looking fabulous and enjoy life to the max.
Over recent years several types of product have hit the market that claim to boost NAD+ back to healthy youthful levels. In this article we review two of the most common types of product available and assess their scientific efficacy.
‘Pure NAD+’ supplements
Some companies sell tablets or powders containing ‘pure NAD+' and advertise them as a method to directly boost your body's NAD+ levels. Sadly, these products can't work as advertised because NAD+ is broken down in the digestive system before it can reach the bloodstream, let alone the cells where it's actually needed.
This is because NAD+ is a big unstable molecule with low bioavailability. That means is has a tough time getting through protective cellular walls, but Mother Nature solves this problem by making NAD+ within the cell right where it’s needed. Anything that calls itself 'pure NAD+' can't boost cellular NAD+ levels and will likely be a waste of your time and money.
Sublingual NAD+ and intravenous NAD+ infusion
People are beginning to realise there's a problem getting NAD+ through the gut and into cells where's it's needed. This has led to growing interest in two methods that offer to boost NAD+ by avoiding the gut altogether.
The first is direct intravenous infusion of NAD+ into the blood and the second is sublingual delivery of NAD+ (absorption directly into the blood via a tablet dissolved under the tongue). Both methods are promoted as ways to bypass the digestive tract and resolve NAD+'s bioavailability problem.
Now, whilst either approach can deliver NAD+ directly into the blood, neither solves the problem of getting NAD+ through protective cellular walls. The NAD+ molecule is too big to pass from blood into the majority of cells where it's needed, so neither direct intravenous infusion or sublingual delivery can be recommended as an effective way to boost cellular NAD+ levels.
NAD+ is a big unstable molecule with low bioavailability. This means is has a tough time surviving in the bloodstream and getting through protective cellular walls. Remember, any product that claims to boost NAD+ must first pass the bioavailability test.
Because the bioavailability problem isn’t fixed, NAD+ molecules in sublingual and intravenous products simply get broken down into other substances and excreted by your body as waste.