When your NAD+ levels are high it makes you feel great and boosts the energy you need to stay strong and enjoy life.
Until recently the only way to boost NAD+ levels with scientific credibility was to supplement with precursors like NR and NMN.
Precursor supplements do actually increase cellular NAD+ levels, which is good, but the boost they give is only modest (40-60%) and hits a premature limit. Precursors like NR and NMN struggle to lift NAD+ back to the high levels young people enjoy, which is what older individuals need for effective cell rejuvenation.
This limitation of precursors has been revealed by scientific data showing that simply increasing the dose of precursor does not mean the body makes more NAD+ (Trammell et al. 2016). To explain why this happens we need to understand the importance of the cellular NAD+ Salvage Pathway and why its gradual failure over time really matters.